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Senior Lecturer in Medicinal Chemistry

I completed my BSc (Hons) degree in Chemical and Pharmaceutical Sciences at the University of Sunderland in 2007, and undertook an industrial placement working at GlaxoSmithKline in the Psychiatry Centre of Excellence for Drug Discovery (CEDD).  This was followed by successful completion of a Master’s degree in Drug Chemistry, graduating from Newcastle University with Distinction.

I began my research career, completing a Cancer Research UK funded PhD under the supervision of Dr Ian Hardcastle, alongside Dr Celine Cano, Prof Roger Griffin and Prof Bernard Golding at the Northern Institute for Cancer Research, Newcastle University in 2012. During this time, I specialised in the field of small-molecule drug discovery, developing inhibitors of the protein kinase ERK5 as potential anti-cancer therapeutics, and went on to spend a further 18 months furthering the project as a Postdoctoral Research Associate.

I then moved to the prestigious Institute of Cancer Research in London (2014), working as a Postdoctoral Research Fellow, alongside Prof Ian Collins, initially working on the lead-optimisation of modulators of IRE-1 – a dual kinase-endoribonuclease enzyme – before taking a leading role in the hit triage, validation and hit-to-lead development of novel inhibitors on an exciting, undisclosed project.

I secured my first academic position at the University of Wolverhampton in 2016, beginning my independent research career as a Lecturer in Pharmaceutical Chemistry. I then moved back to the North East, returning to my home city to take up a position as Senior Lecturer in Medicinal Chemistry at the University of Sunderland in 2017. 

Teaching and supervision

Programme Leader 
  • BSc (Hons) Medicinal Chemistry 

Module Leader
  • BPS210 Organic Chemistry
  • BPS319 Advanced Chemistry

Module Lecturer
  • BPS110 Introduction to Pharmaceutical and Biological Chemistry
  • BPS113 Introduction to Pharmaceutics, Pharmacology and Pharmaceutical Regulation 
  • BPS114 Research and Practical Skills in Biopharmaceutical Sciences (Lecturer)
  • CSC101 Introduction to Chemistry Principles in Cosmetic Science
  • BPS214 Further Research and Practical Skills in Biopharmaceutical Sciences 
  • BPS215 Introductory Medicinal Chemistry 
  • BPS310 Research Project
  • PHA111 Fundamental Principles of Pharmaceutical Chemistry and Formulation 
  • PHA222 Integrated Therapeutics 1: Cardiovascular and Renal Systems

Research interests for potential research students

  • Synthesis and evaluation of natural products as potential therapeutic agents
  • Drug design, hit-to-lead and lead-optimisation strategies
  • Development of small-molecule inhibitors of kinases/kinesins as potential anti-cancer therapeutics


I currently supervise/co-supervise two PhD students, working on organic/medicinal chemistry focused projects alongside Dr Mark Gray.

I am a Member of the Royal Society of Chemistry (MRSC).

In 2019, I was awarded a Northern Accelerator Proof-of-Concept Award to develop novel treatments towards the rare genetic disorders, cystinuria and Wilson's disease.


Jump to: Article | Patents
Number of items: 6.


Miller, Duncan C, Reuillon, Tristan, Molyneux, Lauren, Blackburn, Timothy, Cook, Simon J, Edwards, Noel, Endicott, Jane A, Golding, Bernard T, Griffin, Roger J, Hardcastle, Ian, Harnor, Suzannah J, Heptinstall, Amy, Lochhead, Pamela, Martin, Mathew P, Martin, Nick C, Myers, Stephanie, Newell, David R, Noble, Richard A, Phillips, Nicole, Rigoreau, Laurent, Thomas, Huw, Tucker, Julie A, Wang, Lan-Zhen, Waring, Michael J, Wong, Ai-Ching, Wedge, Stephen R, Noble, Martin E and Cano, Celine (2022) Parallel Optimisation of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain Inhibitor. Journal of Medicinal Chemistry, 65 (9). pp. 6513-6540. ISSN 0022-2623

Myers, Stephanie (2019) Identification of a Novel Orally Bioavailable ERK5 Inhibitor with Selectivity over p38α and BRD4. European Journal of Medicinal Chemistry, 178. pp. 530-543. ISSN 0223-5234

Colombano, Giampiero, Caldwell, John J, Matthews, Thomas Peter, Bhatia, Chitra, Joshi, Amar, McHardy, Tatiana, Mok, Ngai Yi, Newbatt, Yvette, Pickard, Lisa, Strover, Jade, Hedayat, Somaieh, Walton, Michael Ian, Myers, Stephanie, Jones, Alan Morenc, Saville, Harry, McAndrew, Craig, Burke, Rosemary, Eccles, Suzanne, Davies, Faith, Bayliss, Richard and Collins, Ian (2019) Binding to an unusual inactive kinase conformation by highly selective inhibitors of inositol-requiring enzyme 1α kinase-endoribonuclease. Journal of Medicinal Chemistry, 62 (5). pp. 2447-2465. ISSN 0022-2623

Myers, Stephanie, Bawn, Ruth H., Bisset, Louise C., Blackburn, Timothy J., Cottyn, Betty, Molyneux, Lauren, Wong, Ai-Ching, Cano, Celine, Clegg, William, Harrington, Ross. W., Leung, Hing, Rigoreau, Laurent, Vidot, Sandrine, Golding, Bernard T., Griffin, Roger J., Hammonds, Tim, Newell, David R. and Hardcastle, Ian R. (2016) High-Throughput Screening and Hit Validation of Extracellular-Related Kinase 5 (ERK5) Inhibitors. ACS Combinatorial Science, 18 (8). pp. 444-455. ISSN 2156-8952

Myers, Stephanie and Collins, Ian (2016) Recent findings and future directions for interpolar mitotic kinesin inhibitors in cancer therapy. Future Medicinal Chemistry, 8 (4). pp. 463-489. ISSN 1756-8919


Cancer Research Technology Ltd (2016) Pyrrolcarboxamide derivatives for the inhbition of erk5. PCT/GB2015/052707.

This list was generated on Sat Mar 2 06:40:44 2024 GMT.
  • Medicinal chemistry
  • Organic chemistry
  • Drug design, Hit-to-Lead and Lead-optimisation strategies in medicinal chemistry
  • Cancer research
  • Cystinuria and Wilson's disease
Memberships and Affiliations
  • Member of the Royal Society of Chemistry (MRSC)
  • Fellow of the Higher Education Academy (FHEA)

  • BSc (Hons) Chemical and Pharmaceutical Science (University of Sunderland)
  • MSc Drug Chemistry (Newcastle University)
  • PhD Medicinal Chemistry (Newcastle University)
  • Postgraduate Certificate in Academic Practice (University of Wolverhampton/University of Sunderland)

Last updated 28 February 2024