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Senior Lecturer in Pharmaceutics

I am a Senior Lecturer in Pharmaceutics. I obtained my PhD in Drug Delivery and Targeting from UCL School of Pharmacy in London in 2006. I then undertook postdoctoral research positions investigating drug delivery systems for pulmonary delivery of anticancer medicines at Strathclyde Institute of Pharmacy and Biomedical Sciences in Glasgow, and for controlled delivery of HIV microbicides at Queen’s University Belfast.

In 2009, I played a key role in establishing a new School of Pharmacy and Pharmaceutical Sciences at Ulster University and I became the Course Director for MSc in Pharmaceutical Sciences from 2010 till 2015.


Teaching and supervision

MPharm
MSc Pharmaceutical and Biopharmaceutical Formulations
BSc (Hons) Biopharmaceutical Science

Teaching interests
Dosage form design 
Biopharmaceutics and pharmacokinetics
Controlled release drug delivery systems
Nanoformulations
3D tablet printing

PhD supervision
N. Uddin (2017- ) "Nanoparticles as drug delivery vehicles for glioblastoma"

S. Girgis (2016- ) "Development of targeting strategies for metastatic cancer using nanoparticles"
H. Al-Sanaa (2015- ) "Development of novel liposomal gene delivery systems" (Co-supervisor)
D. Abdelkader (2014-2017 ) "Development of particulate carriers for delivery and targeting of biotherapeutics" 
L. Spears (2014-2017 ) "Peptide-loaded, shear sensitive hydrogels as a novel topical delivery system for wound management and repair (Co supervisor)
A. Abuelhana (2014-2016) "The development of a model to inform the appropriate skill mix for pharmacy workforce to achieve the optimisation of both patient outcome and cost effectiveness" (Co supervisor) 
N. Ali (2014-2016) "Synthesis, targeting and triggering of functional nanoplasmids" (Co supervisor) 
A. Sharma (2013-2016 ) "Development of nanoparticulate delivery systems for anti-metastatic Ran-GTPase biotherapeutics"
Y. Haggag (2013-2016 ) "Biodegradable nanoparticles as potential delivery system for anti-metastatic Ran-GTPase peptides" 
N. Craythorne (2010-14 ) "Nanoparticles as potential drug delivery systems for antidiabetic peptide therapeutics" 
A. Winder (2009-2013) "Development and characterisation of anti-biotic loaded, stress sensitive hydrogel materials for topical treatment of colonised ulceration" (Co-supervisor)
G. Bode-Animashaun (2009-2013) Project Title: Development and characterisation of photo-antimicrobial hydrogel materials for topical treatment of colonised ulceration (Co-supervisor)

Research interests for potential research students

  • Pharmaceutical nanotechnology for drug delivery and targeting
  • Biodegradable nanoparticles for delivery and targeting of biotherapeutics with anticancer and antidiabetic activities
  • Vaccine delivery and targeting using nanoformulations
  • Controlled delivery of HIV microbicides
  • Pulmonary delivery of anticancer medicines
  • 3D printing technology for tablet manufacture

Research

My research interests focus on the area of nanomedicine and pharmaceutical nanotechnology including the development of biodegradable nanoparticles via different formulation techniques like a novel microfluidic system for delivery and targeting of biotherapeutics with anticancer and antidiabetic activities such as peptides, proteins, SiRNA and DNA plasmids.I have also developed a recent interest in the area of 3D tablet printing for personalised medicine. I established collaborative links with a number of national and international research groups, and my collaboration with Bradford Institute for Cancer Therapeutics has led to a patent application. I have taken a leading role in developing international relations with academic partners for the University of Sunderland.

Publications

Number of items: 31.

Article

Elsana, Hassan, Olusanya, Temidayo O. B., Carr-Wilkinson, Jane, Darby, Steven, Faheem, Ahmed and Elkordy, Amal (2019) Evaluation of novel cationic gene based liposomes with cyclodextrin prepared by thin film hydration and microfluidic systems. Scientific Reports, 9 (15120).

Uddin, Nazim, Elkordy, Amal and Faheem, Ahmed (2019) Fabrication and physicochemical characterisation of novel pimozide loaded PLGA nanoparticles. British Journal of Pharmacy, 4 (1). pp. 22-23. ISSN 2058-8356

Haggag, Yusuf A, Matchett, Kyle B, Falconer, Robert A, Isreb, Mohammad, Jones, Jason, Faheem, Ahmed, McCarron, Paul and El-Tanani, Mohamed (2019) Novel Ran-RCC1 Inhibitory Peptide-Loaded Nanoparticles Have Anti-Cancer Efficacy In Vitro and In Vivo. Cancers, 11 (2). ISSN 2072-6694

Emran, Mohammed Y., Shenashen, Mohamed A., Mekawy, Moataz, Azzam, Ahmed M., Akhtar, Naeem, Gomaa, Hassenien, Selim, Mahmoud M., Faheem, Ahmed and El-Safty, Sherif-A (2018) Ultrasensitive in-vitro monitoring of monoamine neurotransmitters from dopaminergic cells. Sensors and Actuators B: Chemical, 259. pp. 114-124. ISSN 09254005

Abdelkader, D H, Osman, M. A., El-Gizawy, S. A., Hawthorne, S. J., Faheem, Ahmed and McCarron, P. A. (2018) Effect of poly(ethylene glycol) on insulin stability and cutaneous cell proliferation in vitro following cytoplasmic delivery of insulin-loaded nanoparticulate carriers – A potential topical wound management approach. European Journal of Pharmaceutical Sciences, 114. pp. 372-384. ISSN 0928-0987

Emran, Mohammed Y., Mekawy, Moataz, Akhtar, Naeem, Shenashen, Mohamed A., EL-Sewify, Islam M., Faheem, Ahmed and El-Safty, Sherif-A (2018) Broccoli-shaped biosensor hierarchy for electrochemical screening of noradrenaline in living cells. Biosensors and Bioelectronics, 100. pp. 122-131. ISSN 09565663

Abdelkader, D H, El-Gizawy, Sanaa A, Faheem, Ahmed, McCarron, Paul A and Osman, Mohamed A (2018) Effect of process variables on formulation, in-vitro characterisation and subcutaneous delivery of insulin PLGA nanoparticles: An optimisation study. Journal of Drug Delivery Science and Technology, 43. pp. 160-171. ISSN 17732247

Emran, Mohammed Y., Khalifa, Hesham, Gomaa, Hassanien, Shenashen, Mohamed A., Akhtar, Naeem, Mekawy, Moataz, Faheem, Ahmed and El-Safty, Sherif-A (2017) Hierarchical C-N doped NiO with dual-head echinop flowers for ultrasensitive monitoring of epinephrine in human blood serum. Microchimica Acta, 184 (11). pp. 4553-4562. ISSN 0026-3672

Akhtar, Naeem, Emran, Mohammed Y., Shenashen, Mohamed A., Khalifa, Hesham, Osaka, Tetsuya, Faheem, Ahmed, Homma, Takayuki, Kawarada, Hiroshi and El-Safty, Sherif-A (2017) Fabrication of photo-electrochemical biosensors for ultrasensitive screening of mono-bioactive molecules: the effect of geometrical structures and crystal surfaces. J. Mater. Chem. B, 5 (39). pp. 7985-7996. ISSN 2050-750X

Haggag, Yusuf A., Faheem, Ahmed, Tambuwala, Murtaza M., Osman, Mohamed A., El-Gizawy, Sanaa A., O’Hagan, Barry, Irwin, Nigel and McCarron, Paul A. (2017) Effect of poly(ethylene glycol) content and formulation parameters on particulate properties and intraperitoneal delivery of insulin from PLGA nanoparticles prepared using the double-emulsion evaporation procedure. Pharmaceutical Development and Technology. pp. 1-12. ISSN 1083-7450

Haggag, Yusuf. A, Matchett, Kyle B., Dakirc, El-Habib, Buchanan, Paul, Osman, Mohammed A., Elgizawyb, Sanaa A., El-Tanani, Mohamed, Faheem, Ahmed and McCarron, Paul A. (2017) Nano-encapsulation of a novel anti-Ran-GTPase peptide for blockade of regulator of chromosome condensation 1 (RCC1) function in MDA-MB-231 breast cancer cells. International Journal of Pharmaceutics, 521 (1-2). pp. 40-53. ISSN 0378-5173

Yuen, Hiu-Fung, Chan, Ka-Kui, Platt-Higgins, Angela, Dakir, EL-Habib, Matchett, Kyle B., Ahmed Haggag, Yusuf, Jithesh, Puthen V., Habib, Tanwir, Faheem, Ahmed, Dean, Fennell A., Morgan, Richard, Rudland, Philip S. and El-Tanani, Mohamed (2016) Ran GTPase promotes cancer progression via Met receptormediated downstream signaling. Oncotarget, 7. pp. 75854-75864. ISSN 1949-2553

Abdelkader, D H, Osman, M.A., El-Gizawy, S.A., Faheem, Ahmed and McCarron, P.A. (2016) Characterisation and in vitro stability of low-dose, lidocaine-loaded poly(vinyl alcohol)-tetrahydroxyborate hydrogels. International Journal of Pharmaceutics, 500 (1-2). pp. 326-335. ISSN 0378-5173

Haggag, Yusuf, Abdel-Wahab, Yasser, Ojo, Opeolu, Osman, Mohamed, El-Gizawy, Sanaa, El-Tanani, Mohamed, Faheem, Ahmed and McCarron, Paul (2016) Preparation and in vivo evaluation of insulin-loaded biodegradable nanoparticles prepared from diblock copolymers of PLGA and PEG. International Journal of Pharmaceutics, 499 (1-2). pp. 236-246. ISSN 0378 5173

Abdelkader, D H, Osman, M A, Elgizaway, S A, Faheem, Ahmed and McCarron, P A (2016) The Role of Insulin in Wound Healing Process: Mechanism of Action and Pharmaceutical Applications. Journal of Analytical & Pharmaceutical Research, 2 (1). ISSN 24730831

Chan, Ka Kui, Matchett, Kyle B., McEnhill, Paul M., Dakir, El Habib, McMullin, Mary Frances, El-Tanani, Yahia, Patterson, Laurence, Faheem, Ahmed, Rudland, Philip S., McCarron, Paul A. and El-Tanani, Mohamed (2015) Protein deregulation associated with breast cancer metastasis. Cytokine & Growth Factor Reviews, 26 (4). pp. 415-423. ISSN 1359 6101

Haggag, Yusuf A. and Faheem, Ahmed (2015) Evaluation of nano spray drying as a method for drying and formulation of therapeutic peptides and proteins. Frontiers in Pharmacology, 6. ISSN 1663-9812

Najlah, Mohammad, Parveen, Ishrat, Alhnan, Mohamed Albed, Ahmed, Waqar, Faheem, Ahmed, Phoenix, David A., Taylor, Kevin M.G. and Elhissi, Abdelbary (2014) The effects of suspension particle size on the performance of air-jet, ultrasonic and vibrating-mesh nebulisers. International Journal of Pharmaceutics, 461 (1-2). pp. 234-241. ISSN 03785173

Eng, Matthew, Elkordy, Amal, McCarron, Paul and Faheem, Ahmed (2014) Physical Characterisation as an Insight into a Gene Delivery System Containing Cyclodextrins with Pluronic®-F127 and Folic acid as Non-Viral Vectors. Journal of Current Pharmaceutical Biotechnology, 15 (8). pp. 712-726. ISSN 1389-2010

Matchett, Kyle B., McFarlane, Suzanne, Hamilton, Sophie E., Eltuhamy, Yousef S. A., Davidson, Matthew A., Murray, James T., Faheem, Ahmed and El-Tanani, Mohamed (2014) Ran GTPase in Nuclear Envelope Formation and Cancer Metastasis. Advances in Experimental Medicine and Biology, 773. pp. 323-351. ISSN 0065-2598

Elhissi, A. M. A., Brar, J., Najlah, M, Roberts, S. A., Faheem, Ahmed and Taylor, K. M. G. (2013) An Ethanol-Based Proliposome Technology for Enhanced Delivery and Improved Respirability of Antiasthma Aerosols Generated Using a Micropump Vibrating-Mesh Nebulizer. Journal of Pharmaceutical Technology, Research and Management, 1 (2). pp. 171-180. ISSN 2321-2217

Elhissi, Abdelbary, Hidayat, Kanar, Phoenix, David A., Mwesigwa, Enosh, Crean, StJohn, Ahmed, Waqar, Faheem, Ahmed and Taylor, Kevin M.G. (2013) Air-jet and vibrating-mesh nebulization of niosomes generated using a particulate-based proniosome technology. International Journal of Pharmaceutics, 444 (1-2). pp. 193-199. ISSN 03785173

McCarron, Paul A and Faheem, Ahmed (2010) Nanomedicine-based cancer targeting: a new weapon in an old war. Nanomedicine, 5 (1). pp. 3-5. ISSN 1743-5889

Elkordy, Amal, Essa, E A and Faheem, Ahmed (2009) Applications of spray drying and spray congealing to improve poorly water soluble drug dissolution. The American Association of Pharmaceutical Scientists Journal, 11 (S2). ISSN 1550-7416

Elkordy, Amal and Faheem, Ahmed (2009) Effect of beta-cyclodextrin on stability of crystallized and lyophilized protein. The American Association of Pharmaceutical Scientists Journal, 11 (S2). ISSN 1550-7416

Faheem, Ahmed, Falconer, R. A., Somavarapu, S. and Alpar, H. O. (2007) The Use of Polycaprolactone (PCL) - Polyethylene glycol (PEG) nanoparticles as targeted vaccine delivery systems. Journal of Pharmacy and Pharmacology, 59 (Supp 1). A34-A35. ISSN 2042-7158

Book Section

Faheem, Ahmed and Abdelkader, Dalia H. (2020) Novel drug delivery systems. In: Engineering Drug Delivery Systems. Woodhead Publishing Series in Biomaterials . Elsevier, pp. 1-16. ISBN 9780081025482

Matchett, K. B., McFarlane, S., Hamilton, S. E., Elthuhamy, Y. S. A., Davidson, M. A., Murray, J. T., Faheem, Ahmed and El-Tanani, M. (2014) Ran GTPase in Nuclear Envelope Formation and Cancer Metastasis. In: Cancer Biology and the Nuclear Envelope: Recent Advances May Elucidate Past Paradoxes. Advances in Experimental Medicine and Biology (773). Springer, New York, pp. 323-351. ISBN 978-1-4899-8032-8

Conference or Workshop Item

Elsana, Hassan, Carr-Wilkinson, Jane, Faheem, Ahmed and Elkordy, Amal (2018) Preparation, characterisation and cell transfection of cationic liposomes in gene therapy. In: APS@FIP Conference 2018, 7th September 2018, Glasgow.

Haggag, Yusuf, Osman, Mohamed, El-Gizawy, Sanaa, El-Tanani, Mohamed, McCarron, Paul and Faheem, Ahmed (2016) Application of PLGA/PEG block copolymers for controlled delivery of a novel antimetastatic peptide. In: University of Sunderland 2016 Research Conference, 7 Jan 2016, University of Sunderland, UK.. (Unpublished)

Abdelkader, D H, Osman, M, El-Gizawy, S, McCarron, P and Faheem, Ahmed (2016) In Vitro evaluation of human insulin nanoparticles for topical delivery. In: University of Sunderland 2016 Research Conference, 7 Jan 2016, University of Sunderland, UK.. (Unpublished)

This list was generated on Sun Jun 7 08:16:38 2020 BST.
I am a Fellow of The Higher Education Academy in UK and a member of the Academic Pharmacy Group at the Royal Pharmaceutical Society of Great Britain. Also, I am serving as an Associate Editor for the Journal of Analytical and Pharmaceutical Sciences and as a reviewer for many international journals in the field including the International Journal of Pharmaceutics, Journal of Controlled Release and Pharmaceutical Research Journal.

Last updated 11 June 2019

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