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Professor Amal Ali Elkordy


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Professor of Pharmaceutics

I am a Professor of Pharmaceutics. I have a degree in Pharmacy and an MPhil in Pharmaceutical Technology from the University of Tanta, Egypt. I earned my PhD in Pharmaceutical Technology from the School of Pharmacy, University of Bradford.

I was appointed as a Lecturer in Pharmaceutics at the University of Sunderland where I was promoted to Senior Lecturer in 2009, Reader in 2013 and then Professor in 2019.

I have published a significant number of papers on various fields of pharmaceutics, evident from over 140 publications including journal articles, book chapters, and conference papers. I supervised many PhD students to their successful completion and I'm currently supervising a number of PhD students.

My research is reflected in teaching and accordingly, based on my experience in formulations of both small and large drug molecules. I designed MSc Pharmaceutical and BioPharmaceutical Formulations which is one of the few masters courses in the UK that covers biopharmaceuticals as well as pharmaceuticals.

I am a reviewer for several national and international pharmaceutics journals, and a reviewer for book proposals (Elsevier Publisher and CRS Press). I presented keynote and invited speeches at different conferences worldwide. I also chair scientific sessions at national and international pharmaceutical conferences.

I'm currently a Pharmaceutics Subject External Examiner for the MPharm programme at the University of Portsmouth (2021-2025) and external examiner for MSc Pharmaceutical Technology and Medicines Control at the University of Bradford (2022-2026). I have been appointed as external examiner for MSc Pharmaceutical Science and MSc Pharmaceutical Science with Management Studies (2016-2020), Kingston University. Recently I acted as external examiner for 21 PhD and 1 MSc-by research examinations at different universities in the UK and for 20 PhD/MPhil theses abroad. 

I have written and edited a book (Published by Elsevier in June 2023) on monoclonal antibodies entitled "Formulation of Monoclonal Antibody Therapies: From Lab to Market". 

I have been the recipient of many awards from different conferences and symposia. Due to my expertise in pharmaceutical techniques (eg spray drying), Sunderland was a project partner of the EPSRC/EHDA network with more than 20 partners from industry and academia across the UK.

I attracted funding from overseas governments, engaged externally, and provided consultancy to the pharmaceutical industry.



Teaching and supervision

I am Programme Leader for MSc Pharmaceutical and BioPharmaceutical Formulations. I teach the following topics across MPharm and MSc courses:

  • Solid dosage forms such as tablets and their characterisation
  • Techniques to enhance dissolution of hydrophobic drugs for example solid dispersion, liquisolid formulations and supercritical fluid technology
  • Liposomes and niosomes as drug delivery systems
  • Gene and polymer therapeutics
  • Monoclonal antibody therapies
  • Micro-calorimetry and its applications to study protein formulations


Current PhD students as Director of Studies:

  • Dorcas Aly Uzim: The Formulation of a candidate protein drug via microencapsulation in niosomes and nanoparticles to preserve its bioactivity and integrity.
  • Yaqeen Nadheer Albadri: Formulation and characterisation of mRNA using Liposome -RNA complex with or without cyclodextrins
  • Mohammed Ahmed Altaee: Formulation and characterisation of liposome-RNA complex with hydrophilic polymers

    Recently completed PhD students as Director of Studies:

    • Mohamed Ahmed Attia: (Successfully passed his viva voce, October 2023)
    • "Application of the microfluidic system for formulation of novel liposomal nanovesicles loaded with doxorubicin and natural antioxidants for anti-tumour synergism and formulations stabilisation"
          • Ijeoma Annita Abraham: (Successfully completed, July 2023)
        • "Effects of Beta cyclodextrin and Pluronic F-127 on stability of model proteins: Lysozyme, insulin and antibodies"
      • Li Key Yeo: (Successfully completed, March 2022)
        "Evaluation of niosome formulations containing methylene blue and cinnarizine manufactured by thin film hydration and microfluidic methods"
      • Ashraf Saleh: (Successfully completed, October 2020)
        "Dissolution enhancement of bendroflumethiazide, indapamide, and furosemide diuretics using solid dispersions and self-emulsifying drug delivery systems"
      • Hassan Elsana: (February 2015 – July 2019)
        "Gene delivery systems of carboxymethyl-beta-cyclodextrin in solution and liposomal forms"
      • Safwan Abdel Rahim: (October 2013 – March 2018)
        “Preparation and characterisation of floating tablets to target the stomach”
      • Hoda Javaheri: (February 2013 – October 2017) 
        “Wet granulated liquisolid drug delivery systems with hydrophobic and hydrophilic drugs”
      • Muhammad Irfan Alam: (October 2013 – November 2016)"Formulations to protect some antibiotics from degradation in the stomach"
      • Omar Abu Abed: (October 2013 – November 2016)
      • "Preparation and evaluation of liquid and nanocapsule formulations containing biomolecules"
      • Ammar Said Suliman: (October 2012 – July 2016)
        "Preparation and evaluation of different liquisolid compacts containing model hydrophobic drugs: norfloxacin and cinnarizine"
      • Rita Haj Ahmad: (May 2009 – July 2013)
        "Effects of processing techniques and excipients on integrity and stability of protein formulations"


      Recently completed PhD students as co-supervisor:

      • Samuel Girgis: "Development of targeting strategies for metastatic cancer using nanoparticles"
      • Dina Abed Bakhotmah: “Attempts to synthesis substituted quinolones as antibiotic targets using solid phase techniques”
      • Md Nazim Uddin: "Nanoparticles as drug delivery vehicles for glioblastoma"


      Current PhD students as co-supervisor:

      • Amohammed Zidan Ambarek Alsabai: "Fast-dissolving formulations of levothyroxine to enhance its bioavailability"
      • Yasir Jallawi Mahmod Karkar: "Development of 3D Printed Tablets Containing Thermolabile Drugs"
      • George Abdelmalek: "Implementation of 3D printing technologies in pharmaceutical manufacture of tablets"
      • Ali Amer: "Formulation, characterization, and evaluation of peptide niosome by applying spray drying after using thin film hydration method"
        Current Post Doctoral co-workers:
      • Mohamed Ahmed Attia


    • Previous Post Doctoral co-workers:

      • Li Key Yeo
      • Inigo Rodriguez
      • Amanda Solaiman
      • Temidayo Olusanya


      Awards for students:

      • MPharm project student awarded a prize as one of the finalists in the MGR Award competition (2018) run by Mylan Pharmaceuticals Ltd UK for the project into fast disintegrating tablets.
      • Omar Abu Abed, PhD student, awarded a Thermal Methods Group student bursary for the year 2015 for his research on proteins and micro-calorimerty (Abu Abed, O., Chaw, C.S., Carlile, M., Elkordy, A.A., 2015. Evaluating the effect of pH, buffer conditions, and excipients on conformational stability of trypsin) presented at the 50th Anniversary Conference of the RSC Thermal Methods Group, 30 March-1 April 2015, Churchill College Cambridge, UK.
      • Safwan Abdel Rahim, PhD student, given a recommended poster award at the Science of Medicines Conference, 8-10 September 2014, University of Hertfordshire, Hatfield, for his submitted work: Abdel R.S., Elkordy, A.A., & Carter, P. (2014) Preparation of hydroxyethyl cellulose floating tablets of pentoxifylline as a model drug.
      • MPharm project student given a commended poster award (2012) by GlaxoSmithKline for the project into influences of polymers on stability and bioactivity of spray and freeze-dried proteins.
      • MPharm project student given a commended poster award (2012) by GlaxoSmithKline for the project into liquisolid formulations to enhance spironolactone dissolution.
      • MPharm project student awarded a commended poster award (2011) by the British Pharmaceutical Students’ Association and GlaxoSmithKline for her project into effects of cyclodextrins on stability of DNA. 
      • MPharm project student given a College of Mental Health Pharmacists (CMHP) undergraduate Pharmacy Bursary Award (2010) for pioneering research into gene delivery. This recognition was covered by the media, 2010.
      • MPharm project student given a commended poster award (2010) by the British Pharmaceutical Students' Association and GlaxoSmithKline for a novel in-situ lyophilisation technique to enhance dissolution of poorly water-soluble drugs.
      • MPharm project student given a commended oral presentation award (2008) by the British Pharmaceutical Conference for a project looking at formulations of glibenclamide (an antidiabetic drug) microcrystals.

Research interests for potential research students

  • Gene therapeutics and protein therapeutics 
  • Stabilisation of monoclonal antibodies
  • Dissolution enhancement of hydrophobic drugs: via liquisolid technology and drying techniques with additives
    • Targeted drug therapy and controlled drug release: via gastro-retentive formulations (e.g. effervescent floating tablets to target the stomach)
  • Nanomedicines to enhance drug performance: via formulation of liposomal and niosomal drug delivery systems containing plasmid DNA, hydrophobic drugs, anti-infective drugs, or peptides
  • Orodispersable tablet dosage forms

Research

My research interests include:

  • Formulation, stabilisation, and delivery of peptide, monoclonal antibody and protein drugs (using spray drying, freeze-drying and crystallisation technology)
  • The dissolution enhancement of poorly water-soluble drugs using liquisolid technology, liposomes, and polymeric micelles
  • Non-viral gene delivery systems.


My research aims are: 

  • To overcome challenges that pharmaceutical industries face with formulation of small and large drug molecules into suitable dosage forms for the ultimate aim of patient benefits.
  • To disseminate the research results and outcomes via publications and conference presentations.

Publications

Number of items: 152.

Article

Al Badri, Yaqeen Nadheer, Chaw, Cheng and Elkordy, Amal (2023) Insights into Asymmetric Liposomes as a Potential Intervention for Drug Delivery Including Pulmonary Nanotherapeutics. Pharmaceutics, 15 (294). pp. 1-22. ISSN 1999-4923

Ordonio, Michaella B, Zaki, Randa Mohammed and Elkordy, Amal (2022) Dendrimers-Based Drug Delivery System: A Novel Approach in Addressing Parkinson’s Disease. Future Pharmacology, 2 (4). pp. 415-430.

Attia, Mohamed Ahmed, Essa, Ebtessam Ahmed, Elebyary, Toka Tarek, Faheem, Ahmed Mostafa and Elkordy, Amal (2021) Brief on Recent Application of Liposomal Vaccines for Lower Respiratory Tract Viral Infections: From Influenza to COVID-19 Vaccines. Pharmaceuticals, 14 (11). e1173. ISSN 1424-8247

Arshada, Muhammad Sohail, Zafar, Saman, Yousef, Bushra, Alyassin, Yasmine, Ali, Radeyah, AlAsiri, Ali, Chang, Ming-Wei, Ahmad, Zeeshan, Elkordy, Amal, Faheem, Ahmed and Pitt, Kendal (2021) A review of emerging technologies enabling improved solid oral dosage form manufacturing and processing. Advanced Drug Delivery Reviews (113840). ISSN 0169-409X

Elkordy, Amal, Haj-Ahmad, Rita Rushdi, Awaad, Amani S. and Zaki, Randa Mohammed (2021) An overview on natural product drug formulations from conventional medicines tonanomedicines: past, present and future. Journal of Drug Delivery Science and Technology, 63 (102459). ISSN 1773-2247

Abu Abed, Omar S., Mulkala, Srilikha, Sharif, Israa, Abdin, Asma M. and Elkordy, Amal (2021) Lyophilization-free proliposomes for sustained release oral delivery of hydrophobic drug (cinnarazine): a comparative study. Pharmaceutical Technology in Hospital Pharmacy, 6 (1). ISSN 2365-242X

Essa, Ebtessam Ahmed, Elebyary, Toka T, Abdelquader, Magdy M, El Maghraby, Gamal M and Elkordy, Amal (2021) Smart liquids for oral controlled drug release: An overview of alginate and non-alginate based systems. Journal of Drug Delivery Science and Technology. ISSN 1773-2247

Abu Abed, Omar S, Chaw, Cheng, Williams, Lee and Elkordy, Amal (2021) PEGylated polymeric nanocapsules for oral delivery of trypsin targeted to the small intestines. International Journal of Pharmaceutics, 592 (120094). ISSN 0378-5173

Saleh, Ashraf, Elkordy, Amal, Chaw, Cheng, McGarry, Kenneth and Essa, Ebtessam (2020) Insights into the Effect of Trehalose and Cyclodextrin Molecules on Dissolution Characteristics of Furosemide Lyophilised Powder. Open Access Journal of Pharmaceutical Research, 4. ISSN 2574-7797

Saleh, Ashraf, Elkordy, Amal, Chaw, Cheng, McGarry, Kenneth and Childs, Stephen (2020) Feasibility of Self-Emulsifying Drug Delivery System for Dissolution Enhancement of Indapamide. Global Drugs and Therapeutics, 5 (4). ISSN 2399-9098

Attia, Mohamed, Essa, Ebtessam Ahmed, Zaki, Randa Mohammed and Elkordy, Amal (2020) An Overview of the Antioxidant Effects of Ascorbic Acid and Alpha Lipoic Acid (in Liposomal Forms) as Adjuvant in Cancer Treatment. Antioxidants, 9 (359). pp. 1-15. ISSN 2076-3921

Elsana, Hassan, Olusanya, Temidayo O. B., Carr-Wilkinson, Jane, Darby, Steven, Faheem, Ahmed and Elkordy, Amal (2019) Evaluation of novel cationic gene based liposomes with cyclodextrin prepared by thin film hydration and microfluidic systems. Scientific Reports, 9 (15120).

Said Suliman, Ammar, Anderson, Rosaleen and Elkordy, Amal (2019) Preparation of novel optimum liquisolid compacts via incorporating water granulation process to enhance the powder characterizations and dissolution behavior of a poorly soluble drug: Norfloxacin. Powder Technology. ISSN 0032-5910

Uddin, Nazim, Elkordy, Amal and Faheem, Ahmed (2019) Fabrication and physicochemical characterisation of novel pimozide loaded PLGA nanoparticles. British Journal of Pharmacy, 4 (1). pp. 22-23. ISSN 2058-8356

Yeo, Li Key, Chaw, Cheng and Elkordy, Amal (2019) The Effects of Hydration Parameters and Co-Surfactants on Methylene Blue-Loaded Niosomes Prepared by the Thin Film Hydration Method. Pharmaceuticals, 12(2) (46).

Yeo, Li Key, Olusanya, Temidayo O.B., Chaw, Cheng and Elkordy, Amal (2018) Brief Effect of a Small Hydrophobic Drug (Cinnarizine) on the Physicochemical Characterisation of Niosomes Produced by Thin-Film Hydration and Microfluidic Methods. Pharmaceutics, 10 (4). p. 185. ISSN 1999-4923

Abu Abed, Omar S, Chaw, Cheng, Wiilliams, Lee and Elkordy, Amal (2018) Lysozyme and DNase I loaded poly (D, L lactide-co-caprolactone) nanocapsules as an oral delivery system. Scientific Reports. ISSN 2045-2322

Olusanya, Temidayo, Haj Ahmad, Rita, Ibegbu, Daniel, Smith, James and Elkordy, Amal (2018) Liposomal Drug Delivery Systems and Anticancer Drugs. Molecules, 23 (4). p. 907. ISSN 1420-3049

Elsana, Hassan, Mysina, Svetlana, Elkordy, Emal Ali, Carr-Wilkinson, Jane and Elkordy, Amal (2018) Insights into the influences of carboxymethyl-β-cyclodextrin on DNA formulations characteristics and gene transfection efficiency. Current Drug Delivery, 15 (6). pp. 867-878. ISSN 1567 2018

Saleh, Ashraf, McGarry, Kenneth, Chaw, Cheng and Elkordy, Amal (2018) Feasibility of using gluconolactone, trehalose and hydroxy-propyl gamma cyclodextrin to enhance bendroflumethiazide dissolution using lyophilisation and physical mixing techniques. Pharmaceutics, 10 (1). pp. 1-16. ISSN 1999-4923

Abdel Rahim, S., Carter, Paul and Elkordy, Amal (2017) Influence of calcium carbonate and sodium carbonate as gassing agents on pentoxifylline floating tablets properties. Powder Technology Journal, 322. pp. 65-74. ISSN 0032-5910

Solaiman, Amanda, Tatari, A.K. and Elkordy, Amal (2017) Naproxen Microparticulate Systems Prepared Using In Situ Crystallisation and Freeze-Drying Techniques. AAPS PharmSciTech - Invited article, 18 (5). pp. 1438-1446. ISSN 1530-9932

Haj-Ahmad, Rita, Mamayusupov, M., Elkordy, E. A. and Elkordy, Amal (2016) Influences of copolymers (Copovidone, Eudragit RL PO and Kollicoat MAE 30 DP) on stability and bioactivity of spray-dried and freeze-dried lysozyme. Drug Development and Industrial Pharmacy, 42 (12). ISSN 0363-9045

Abu Abed, O. S., Elkordy, Amal, Chaw, Cheng, Williams, Lee and Carlile, Mark (2016) Development and Characterisation of Polymeric Nanacapsules Containing Macromolecule. Molecular Therapy, 24 (Supp 1). S237-S238. ISSN 1525-0016

Alam, Muhammad Irfan, Paget, Timothy and Elkordy, Amal (2016) Characterisation of furazolidone-chitosan based spray dried microparticles regarding their drug release and mucin adsorptive properties. Powder Technology, 295. pp. 175-179. ISSN 0032-5910

Solaiman, Amanda, Suliman, Ammar Said, Shinde, Swapnil, Naz, Sidra and Elkordy, Amal (2016) Application of general multilevel factorial design with formulation of fast disintegrating tablets containing croscaremellose sodium and Disintequick MCC-25. International Journal of Pharmaceutics, 501 (1-2). pp. 87-95. ISSN 0378-5173

Alam, Muhammad Irfan, Paget, Timothy and Elkordy, Amal (2016) Formulation and advantages of furazolidone in liposomal drug delivery systems. European Journal of Pharmaceutical Sciences, 84. pp. 139-145. ISSN 0928-0987

Haj-Ahmad, Rita, Elkordy, Amal and Chaw, Cheng (2015) In vitro characterisation of Span 65 niosomal formulations containing proteins. Current Drug Delivery Journal, 12 (5). 628-639(12). ISSN 1875-5704

Haj-Ahmad, Rita, Chen, Y. T. and Elkordy, Amal (2015) An overview for the effects of lactitol, gelucire 44/14 and copovidone on lysozyme biological activity. European Journal of Biomedical and Pharmaceutical Sciences (EJBPS), 2 (3). pp. 1328-1339. ISSN 2349-8870

Abdel Rahim, S., Carter, Paul and Elkordy, Amal (2015) Design and evaluation of effervescent floating tablets based on hydroxyethyl cellulose and sodium alginate using pentoxifylline as a model drug. Drug Design, Development and Therapy, 9. pp. 1843-1857. ISSN 1177-8881

Abdel Rahim, S. and Elkordy, Amal (2015) Formulation and evaluation of different floating tablets containing metronidazole to target stomach. Current Drug Delivery Journal, 12 (4). ISSN 1567-2018

Loh, Z.C. and Elkordy, Amal (2015) Formulation and evaluation of different floating tablets containing metronidazole to target stomach. Current Drug Delivery Journal, 12 (4). pp. 425-443. ISSN 1567-2018

Javaheri, H., Carter, Paul and Elkordy, Amal (2014) Wet granulation to overcome liquisolid technique issues of poor flowability and compactibility: A study to enhance Glibenclamide dissolution. Journal of Pharmaceutics and Drug Development, 1 (5). pp. 501-512. ISSN 2348-9782

Said Suliman, Ammar, Anderson, Rosaleen and Elkordy, Amal (2014) Norfloxacin as a model hydrophobic drug with unique release from liquisolid formulations prepared with PEG200 and Synperonic PE/L-61 non-volatile liquid vehicles. Powder Technology, 257. pp. 156-167. ISSN 0032-5910

Eng, Matthew, Elkordy, Amal, McCarron, Paul and Faheem, Ahmed (2014) Physical Characterisation as an Insight into a Gene Delivery System Containing Cyclodextrins with Pluronic®-F127 and Folic acid as Non-Viral Vectors. Journal of Current Pharmaceutical Biotechnology, 15 (8). pp. 712-726. ISSN 1389-2010

Crum, Matthew, Elkordy, Amal, Zarara, Moataz and Elkordy, Eman Ali (2013) In situ lyophilisation of nifedipine directly in hard gelatine capsules. Pharmaceutical Development and Technology, 18 (6). pp. 1379-1390. ISSN 1097-9867

Elkordy, Amal, Bhangale, U, Murle, N and Zarara, M F (2013) Combination of Lactose (as a carrier) with Cremophor® EL (as a liquid vehicle) to Enhance Dissolution of Griseofulvin. Powder Technology, 246. pp. 182-186. ISSN 0032-5910

Elkordy, Amal, Tan, N X and Essa, E A (2013) Spironolactone release from liquisolid formulations prepared with CapryolTM90, Solutol®HS-15 and Kollicoat®SR 30D as non-volatile liquid vehicles. European Journal of Pharmaceutics and Biopharmaceutics, 83 (3). 203-223.. ISSN 0939-6411

Haj-Ahmad, Rita, Elkordy, Amal, Chaw, Cheng and Moore, Adrian (2013) Compare and contrast the effects of surfactants (Pluronic®F-127 and Cremophor®EL) and sugars (beta-cyclodextrin and inulin) on properties of spray dried and crystallised lysozyme. European Journal of Pharmaceutical Sciences, 49 (4). pp. 519-534. ISSN 0928-0987

Elkordy, Amal, Ashoore, Amin and Essa, Ebtessam Ahmed (2012) Complexation of naproxen with beta-cyclodextrin with and without poloxamer 407 to enhance drug dissolution. Journal of Applied Pharmacy, 03 (04). pp. 614-627.

Eng, Matthew and Elkordy, Amal (2012) Gene delivery using non-viral vectors (cyclodextrins) with pluronic-F127 and folic acid. Proceedings of the Second Electronic Conference on Pharmaceutical Sciences, Sciforum Electronic Conferences Series. pp. 1-39.

Elkordy, Amal, Jatto, A and Essa, E A (2012) In situ controlled crystallization as a tool to improve the dissolution of Glibenclamide. International Journal of Pharmaceutics, 428 (1-2). pp. 118-120. ISSN 0378-5173

Elkordy, Amal, Essa, Ebtessam Ahmed, Dhuppad, Shreyas and Jammigumpula, Poojitha (2012) Liquisolid technique to enhance and to sustain griseofulvin dissolution: Effect of choice of non volatile liquid vehicles. International Journal of Pharmaceutics, 434 (1-2). pp. 122-132. ISSN 0378-5173

Beba, H M and Elkordy, Amal (2011) Carrier systems in gene delivery - progressive research in mental health pharmacy. Clinical Pharmacist, 3 (3). S2-S3. ISSN 1352-7967

Adeusi, T, Haj Ahmad, R and Elkordy, Amal (2010) Crystallisation of furosemide using different solvents to enhance drug dissolution. Journal of Pharmacy and Pharmacology, 62 (10). pp. 1256-1257. ISSN 0022-3573

Beba, H M and Elkordy, Amal (2010) Cyclodextrins with pluronic F-127 as carrier systems in gene delivery using drying technology. Journal of Pharmacy and Pharmacology, 62 (10). pp. 1257-1258. ISSN 2042-7158

Crum, M. and Elkordy, Amal (2010) Effect of excipient co-povidone prepared by in-situ lyophilisation and spray drying on nifedipine dissolution. Journal of Pharmacy and Pharmacology, 62 (10). pp. 1422-1423. ISSN 0022-3573

Haj Ahmad, R, Chaw, Cheng and Elkordy, Amal (2010) Niosomes with span 65 and pluronic F-127 as a novel delivery system for lysozyme. Journal of Pharmacy and Pharmacology, 62 (10). pp. 1453-1454. ISSN 2042-7158

Akinlade, Babatunde, Elkordy, Amal, Essa, E A and Elhagar, S (2010) Liquisolid Systems to Improve the Dissolution of Furosemide. Scientia Pharmaceutica, 78 (2). pp. 325-344. ISSN 0036-8709

Elkordy, Amal and Ebtessam, A (2010) Dissolution of ibuprofen from spray dried and spray chilled particles. Pakistan Journal of Pharmaceutical Sciences, 23 (3). pp. 284-290. ISSN 1011-601X

Tatari, A and Elkordy, Amal (2010) In-situ microcrystallisation and improvement of hydrophobic drug dissolution. The American Association of Pharmaceutical Scientists Journal, 12 ((S2)). R6018. ISSN 1550-7416

Tiong, Ngiik and Elkordy, Amal (2009) Effects of liquisolid formulations on dissolution of naproxen. European Journal of Pharmaceutics and Biopharmaceutics, 73 (3). pp. 373-384. ISSN 0939-6411

Michie, A and Elkordy, Amal (2009) Characterisation of spray-dried naproxen formulations. Journal of Pharmacy and Pharmacology, 61 (Supp 1). A56-A57. ISSN 2042-7158

Rahmou, A. and Elkordy, Amal (2009) Effects of surfactants on integrity and biological activity of crystallised and spray-dried proteins. Journal of Pharmacy and Pharmacology, 61 (Supp.1). A23. ISSN 0022-3573

Lambe, C and Elkordy, Amal (2009) Improving dissolution properties of griseofulvin using solid dispersion systems with Solutol HS15 and Acconon CO-7. Journal of Pharmacy and Pharmacology, 61 (Sup 1). A63-A64. ISSN 2042-7158

Elkordy, Amal, Essa, E A and Faheem, Ahmed (2009) Applications of spray drying and spray congealing to improve poorly water soluble drug dissolution. The American Association of Pharmaceutical Scientists Journal, 11 (S2). ISSN 1550-7416

Elkordy, Amal and Faheem, Ahmed (2009) Effect of beta-cyclodextrin on stability of crystallized and lyophilized protein. The American Association of Pharmaceutical Scientists Journal, 11 (S2). ISSN 1550-7416

Tiong, N and Elkordy, Amal (2009) Liquisolid Tablets and Enhancement of Naproxen Dissolution. Journal of Pharmacy and Pharmacology, S1. A58 -A59. ISSN 2042-7158

Osman, N F, Holyoake, T, Zeineldin, A, Elkordy, Amal and McQuaker, I G (2009) TNF Polymorphisms independently predict outcome in patients with B-Cell non-Hodgkin's Lymphoma. Iranian Journal of Cancer Prevention, 2 (1). pp. 19-27. ISSN 2008-2398

Dodou, Kalliopi and Elkordy, Amal (2008) Enhanced in-Vitro Release of Glibenclamide from Drug-in-Adhesive Silicone Layers Using Solid-Dispersions of Glibenclamide with Solutol-Hs15. Journal of Pharmacy and Pharmacology, 60 (S1). A39-A39. ISSN 2042-7158

Jatto, A and Elkordy, Amal (2008) Preparation and characterisation of glibenclamide microcrystals. Journal of Pharmacy and Pharmacology, 60 (S1). A14. ISSN 2042-7158

Wong, Kim and Elkordy, Amal (2008) Utilisation of non-ionic amphiphilic surfactants to enhance dissolution of naproxen from capsule dosage forms. Journal of Pharmacy and Pharmacology, 60 (S1). A39. ISSN 2042-7158

Elkordy, Amal, Forbes, Robert T and Barry, Brian W (2008) Study of protein conformational stability and integrity using calorimetry and FT-Raman spectroscopy correlated with enzymatic activity. European Journal of Pharmaceutical Sciences, 33 (2). pp. 177-190. ISSN 0928-0987

Elkordy, Amal, Forbes, Robert T and Barry, Brian W (2007) Preparation and characterisation of spray-dried and crystallised trypsin: FT-Raman study to detect protein denaturation after thermal stress. European Journal of Pharmaceutical Sciences, 30 (3-4). pp. 315-323. ISSN 09280987

Elkordy, Amal, Hodges, Lee Ann and Mullen, Alex B (2006) Dissolution enhancement of spironolactone by in situ lyophilisation. Journal of Pharmacy and Pharmacology, 58. ISSN 00316873

Elkordy, Amal, Forbes, Robert T and Barry, Brian W (2004) Stability of crystallised and spray-dried lysozyme. International Journal of Pharmaceutics, 278 (2). pp. 209-219. ISSN 03785173

Elkordy, Amal, Forbes, Robert T and Barry, Brian W (2002) Integrity of crystalline lysozyme exceeds that of a spray-dried form. International Journal of Pharmaceutics, 247 (1-2). pp. 79-90. ISSN 03785173

Book Section

Elkordy, Amal, Elsayed, Moustafa, Al-Abdulrazag, Sohib Bashier and Zarara, Zeinab Moataz (2023) Application of approved and marketed products of monoclonal antibody therapies. In: Formulation of Monoclonal Antibody Therapies: From Lab to Market. Elsevier, pp. 287-327. ISBN 9780128233658

Elkordy, Amal and Singh, Kamalinder K. (2023) Biosimilar antibodies. In: Formulation of Monoclonal Antibody Therapies: From Lab to Market. Elsevier, pp. 39-52. ISBN 9780128233658

Faltes, Marc and Elkordy, Amal (2023) Industrial aspects of finished monoclonal antibody therapies. In: Formulation of Monoclonal Antibody Therapies: From Lab to Market. Elsevier, pp. 259-285. ISBN 9780128233658

Elkordy, Amal and Carlile, Mark (2023) Introduction about monoclonal antibodies. In: Formulation of Monoclonal Antibody Therapies: From Lab to Market. Elsevier, pp. 1-38. ISBN 9780128233658

Elkordy, Amal and Chaw, Cheng (2023) Pharmaceutical aspects of mAbs: formulation, characterization, and current route of administration of monoclonal antibody therapies. In: Formulation of Monoclonal Antibody Therapies: From Lab to Market. Elsevier, pp. 53-207. ISBN 9780128233658

Elkordy, Amal, Parveen, Amerah and Haj-Ahmad, Rita (2023) Route of monoclonal antibodies administration. In: Formulation of Monoclonal Antibody Therapies: From Lab to Market. Elsevier, pp. 209-258. ISBN 9780128233658

Elsana, Hassan and Elkordy, Amal (2022) Viral and non-viral nanoparticles for gene therapeutics. In: Bionanotechnology: Next-Generation Therapeutic Tools. Bentham, pp. 159-176. ISBN 978-981-5051-28-5

Goel, Honey, Saini, Komal, Razdan, Karan, Khurana, Rajneet Kaur, Elkordy, Amal and Singh, Kamalinder K. (2022) In vitro physicochemical characterization of nanocarriers: a road to optimization. In: Nanoparticle Therapeutics. Elsevier, pp. 133-179. ISBN 9780128207574

Goel, Honey, Saini, Komal, Razdan, Karan, Khurana, Rajneet Kaur, Elkordy, Amal and Singh, Kamalinder K. (2021) In vitro physicochemical characterization of nanocarriers: a road to optimization. In: Nanoparticle Therapeutics Production Technologies, Types of Nanoparticles, and Regulatory Aspects. Elsevier, pp. 133-180. ISBN 9780128207574

Abraham, Ijeoma, Elkordy, Eman Ali, Haj-Ahmad, Rita, Ahmad, Zeeshan and Elkordy, Amal (2019) Effect of Spray-Drying and Electrospraying as Drying Techniques on Lysozyme Characterisation. In: Electrospinning and Electrospraying - Techniques and Applications. IntechOpen Limited Publisher.

Abdel Rahim, S. and Elkordy, Amal (2016) Application of Xanthan Gum as a Sustained Release Agent. In: Xanthan Gum: Applications and Research Studies. Nova Science Publishers, Inc., New York, New York, pp. 67-96. ISBN 9781536100105

Elkordy, Amal, Forbes, R.T. and Barry, B.W. (2013) Determination of Folding Reversibility of Lysozyme Crystals using Microcalorimetry. In: Application of Calorimetry in a Wide Context: Differential scanning calorimetry, Isothermal titration calorimetry and microcalorimetry. InTech-Europe, pp. 185-196. ISBN 978-953-51-0947-1

Conference or Workshop Item

Karkara, Yasir, Elkordy, Amal and Faheem, Ahmed (2023) 3D printed flexible design for personalized drug release. In: 14th APS PharmSci International Conference, 05-07 Sep 2023, Reading University, Reading, UK.

Attia, Mohamed, Hill, David and Elkordy, Amal (2023) Application of microfluidic system for preparation of liposomal anti-tumour co-loaded with natural antioxidants for anti-tumour synergism and formulation stabilisation. In: 14th APS PharmSci International Conference, 05-07 Sep 2023, Reading University, Reading, UK.

Attia, Mohamed, Hill, David, Chaw, Cheng and Elkordy, Amal (2023) Novel combinational liposomal formulations to treat psoriasis and atopic dermatitis. In: 14th APS PharmSci International Conference, 5th -7th September 2023, Reading University, Reading, UK.

Karkara, Yasir, Elkordy, Amal and Faheem, Ahmed (2023) Three-dimensional printing of flexible polypill. In: 14th APS PharmSci International Conference, 05-07 Sep 2023, Reading University, Reading, UK.

Uddin, Nazim, Elkordy, Amal and Faheem, Ahmed (2022) Novel Formulation of PGLA nanoparticles for targeted glioblastoma chemotherapy. In: UNSPECIFIED.

Yeo, Li Key, Chaw, Cheng and Elkordy, Amal (2019) Analysis of novel mucoadhesive microfluidic-based niosomes. In: UNSPECIFIED, 11th - 13th September 2019, Royal Naval College, Greenwich, London.

Gkotsopoulou, Sofia, Elkordy, Eman Ali and Elkordy, Amal (2019) Formulation and characterization of new fast disintegrating tablets. In: UNSPECIFIED, 11th - 13th September 2019, Royal Naval College, Greenwich, London.

Haj Ahmad, Rita, Elkordy, Amal and Al-Abboodi, Adian (2019) Preparation and characterisation of niosomes containing methylene blue. In: UNSPECIFIED, 11th - 13th September 2019, Royal Naval College, Greenwich, London.

Abraham, Ijeoma and Elkordy, Amal (2018) Formulation and stability of lysozyme. In: The AAPS PharmSci 360 Conference 2018, 4 - 7 Nov 2018, Walter E. Washington Convention Centre, Washington, DC, USA..

Yeo, Li Key, Chaw, Cheng and Elkordy, Amal (2018) Effects of preparation methods on the characteristics of niosomes. In: APS@FIP Conference 2018, 7th September 2018, Glasgow.

Mulkala, Srilekha, Olusanya, Temidayo and Elkordy, Amal (2018) Formulation and characterisation of liposomes with cinnarizine. In: APS@FIP Conference 2018, 7th September 2018, Glasgow.

Elsana, Hassan, Carr-Wilkinson, Jane, Faheem, Ahmed and Elkordy, Amal (2018) Preparation, characterisation and cell transfection of cationic liposomes in gene therapy. In: APS@FIP Conference 2018, 7th September 2018, Glasgow.

Yeo, Li Key, Chaw, Cheng and Elkordy, Amal (2018) Microfluidic-based preparations of novel niosomal formulations for entrapment of cinnarizine as a model poorly water soluble drug. In: 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 19-22 Mar 2018, Granada, Spain. (Unpublished)

Abraham, Ijeoma A., Elkordy, Eman A., Alshahrani, Abdulrahman M. and Elkordy, Amal (2016) Investigation of crystallized and spray dried lysozyme in the absence and presence of Cremophor RH 40 and Solutol HS 15 (as Surfactants). In: The EPSRC EHDA Network: International Pharmaceutical Technology Conference,, 4 Nov 2016, DeMontfort University, Leicester, UK. (Unpublished)

Albayati, Mustafa, Suliman, Ammar S. and Elkordy, Amal (2016) Novel liposomal formulations for entrapment of cinnarizine. In: The EPSRC EHDA Network: International Pharmaceutical Technology Conference, 4 Nov 2016, DeMontfort University, Leicester, UK. (Unpublished)

Alhoushy, AbdalRahman, Suliman, Ammar S. and Elkordy, Amal (2016) Optimization of oro-dispersible tablets using hydroxypropyl cellulose as a disintegrant. In: The EPSRC EHDA Network: International Pharmaceutical Technology Conference, 4 Nov 2016, DeMontfort University, Leicester, UK. (Unpublished)

Sandhu, K., Javaheri, H., Essa, E.A. and Elkordy, Amal (2016) Preparation and characterisation of floating tablets containing cinnarizine. In: 7th APS International PharmSci 2016; Pharmaceutical Sciences: Improving World Health, 5 – 7 Sep 2016, Technology and Innovation Centre, Strathclyde, Glasgow, UK. (Unpublished)

Saleh, Ashraf, Chaw, Cheng, McGarry, Kenneth and Elkordy, Amal (2016) Self-emulsifying drug delivery systems (SEDDS) to improve dissolution of bendroflumethiazide. In: The 7th APS International PharmSci 2016; Pharmaceutical Sciences: Improving World Health, 5 – 7 Sep 2016, Technology and Innovation Centre, Strathclyde, Glasgow, UK. (Unpublished)

Elsana, H, Carr-Wilkinson, Jane and Elkordy, Amal (2016) Carboxymethyl beta cyclodextrin to protect DNA formulations. In: 10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 4-7 Apr 2016, Scottish Exhibition + Conference Centre, Glasgow, UK. (Unpublished)

Elsana, Hassan, Carr-Wilkinson, Jane and Elkordy, Amal (2016) Effects of cyclodextrin on DNA formulations: A preliminary study for gene therapeutics. In: Research Conference, 7 Jan 2016, University of Sunderland, UK.. (Unpublished)

Salem, A and Elkordy, Amal (2016) Liposomal Domperidone formulations. In: 10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 4-7 Apr 2016, Scottish Exhibition + Conference Centre, Glasgow, UK. (Unpublished)

Chen, Yean Teng and Elkordy, Amal (2016) Lysozyme stability in solution forms. In: 10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 4-7 Apr 2016, Scottish Exhibition + Conference Centre, Glasgow, UK. (Unpublished)

Javaheri, H., Elkordy, Amal and Carter, Paul (2015) Dissolution study of liquisolid compacts containing metformin: Overcoming the issue of poor powder flowability and compactibility using wet granulation technique. In: 6th APS International PharmSci 2015, Innovation in Pharmaceutical Sciences, 7 - 9 Sept 2015, East Midlands Conference Centre, Nottingham, UK. (Unpublished)

Surianarayanan, U. D. and Elkordy, Amal (2015) Formulation and characterization of fast disintegrating tablets with Furosemide. In: 6th APS International PharmSci 2015, Innovation in Pharmaceutical Sciences, 7 - 9 Sept 2015, East Midlands Conference Centre, Nottingham, UK. (Unpublished)

Rezwana, S. A. and Elkordy, Amal (2015) Designing of some floating tablets. In: 42nd Annual Meeting & Exposition of the Controlled Release Society, 26-29 July 2015, Edinburgh, Scotland. (Unpublished)

Salem, A., Bhatia, P., Vasseur, A. and Elkordy, Amal (2015) Effect of polyethyleneglycol bisphenol A epichlorohydrin copolymer and gluconolactone on trypsin biological activity. In: 42nd Annual Meeting & Exposition of the Controlled Release Society, 26-29 July 2015, Edinburgh, Scotland. (Unpublished)

Elkordy, Amal (2015) A case study to reflect academic views on how student engagement shapes the student future. In: Three Rivers Learning and Teaching Conference: Student Engagement, 27 Mar 2015, St Peter's Campus, University of Sunderland, UK. (Unpublished)

Morgan, Y. R., Al Meanazel, O., Ali, L. and Elkordy, Amal (2015) Characterization of DNA complexes with cyclodextrin and polyethyleneglycol bisphenol A as potential formulations for gene therapy. In: 42nd Annual Meeting & Exposition of the Controlled Release Society, 26-29 July 2015, Edinburgh, Scotland. (Unpublished)

Mustafa, M. O., Hatemi, E., Hatemi, A. and Elkordy, Amal (2015) Effect of gluconolactone and polyethyleneglycol bisphenol A epichlorohydrin copolymer with lysozyme solution. In: 42nd Annual Meeting & Exposition of the Controlled Release Society, 26-29 July 2015, Edinburgh, Scotland. (Unpublished)

Abu Abed, O. S., Chaw, Cheng, Carlile, Mark, Williams, Lee and Elkordy, Amal (2015) Effects of copolymer type and excipient on the size and encapsulation efficiency of lysozyme containing nanocapsules. In: 6th APS International PharmSci 2015, Innovation in Pharmaceutical Sciences, 7 - 9 Sept 2015, East Midlands Conference Centre, Nottingham, UK. (Unpublished)

Abu Abed, O. S., Chaw, Cheng, Carlile, Mark and Elkordy, Amal (2015) Evaluating the effect of pH, buffer conditions, and excipients on conformational stability of trypsin. In: 50th Anniversary Conference of the RSC Thermal Methods Group, 30 Mar - 1 Apr 2015, Churchill College, Cambridge, UK. (Unpublished)

Palmer, R. and Elkordy, Amal (2015) Feasibility of using Lubritose SD to enhance properties of Piracetam floating tablets. In: 6th APS International PharmSci 2015, Innovation in Pharmaceutical Sciences, 7 - 9 Sept 2015, East Midlands Conference Centre, Nottingham, UK. (Unpublished)

Hadjipour, Azhidhack, Palmer, Rena-Jean, Zarara, Mohamed and Elkordy, Amal (2015) Floating Drug Delivery Systems with Xanthan Gum, Eudragit-RS PO or Lubritose SD: Nizatidine and Piracetam as Model Drugs. In: 1st International Electronic Conference on Medicinal Chemistry, 2-27 Nov 2015, Internet-based. (Submitted)

Elkordy, Amal (2015) Formulation of liposomal drug delivery systems. In: Enhancing Nanoparticle Formulation & Scale Up: Microfluidics Users-group meeting, 3 Nov 2015, Aston University, Birmingham, UK. (Unpublished)

Suliman, A.S., Anderson, Rosaleen and Elkordy, Amal (2015) Liquisolid technique in combination with wet granulation process for improving norfloxacin dissolution. In: Formulation and Drug Delivery Conference 2015, 18-19 May 2015, Kensington Close Hotel, London, UK. (Unpublished)

Elkordy, Amal (2014) Liquisolid tablets: from the laboratory to the market. In: Invited Speaker, Research Seminar, 27th November 2014, University of Bradford, Bradford School of Pharmacy, Bradford, UK. (Unpublished)

Saleh, A., Elkordy, Amal and McGarry, Kenneth (2014) Dissolution Enhancement of Bendroflumethiazide Using Gluconolactone, gamma-cyclodextrin, Trehalose. In: APS PharmSci2014: The Science of Medicines, 8 - 10 Sep 2014, Univerity of Hertfordshire, Hatfield. (Unpublished)

Abdel Rahim, S., Elkordy, Amal and Carter, Paul (2014) Effect of different gas forming agents on characteristics of floating tablets. In: APS PharmSci2014: The Science of Medicines, 8 - 10 Sep 2014, Univerity of Hertfordshire, Hatfield. (Unpublished)

Alam, M-I., Elkordy, Amal and Paget, Timothy (2014) Enhanced dissolution profile of poorly water soluble furazolidone by different methods. In: APS PharmSci2014: The Science of Medicines, 8 - 10 Sep 2014, Univerity of Hertfordshire, Hatfield. (Unpublished)

Haj-Ahmad, Rita, Chaw, Cheng and Elkordy, Amal (2014) In Vitro Release and stability of Insulin from spanTM 65 Niosomes. In: APS PharmSci2014: The Science of Medicines, 8 - 10 Sep 2014, Univerity of Hertfordshire, Hatfield. (Unpublished)

Abdel Rahim, S., Elkordy, Amal and Carter, Paul (2014) Preparation of hydroxyethyl cellulose floating tablets of pentoxifylline as a model drug. In: APS PharmSci2014: The Science of Medicines, 8 - 10 Sep 2014, Univerity of Hertfordshire, Hatfield. (Unpublished)

Elkordy, Amal (2014) Formation and Characterisation of Spray Dried Protein Particles containing different Polymers. In: BUCHI Spray Drying & Encapsulation Seminar, 2 Jul 2014, King’s College London, UK.

Elkordy, Amal (2014) Is there a considerable need for biosimilars? In: 2nd Annual Biosimilars & Biobetters Congress, 3 - 4 April 2014, London. (Submitted)

Elkordy, Amal (2013) Evaluation of different Floating Tablets. In: Target meeting's Third World Drug Discovery Online Conference, 15 - 17 Oct 2013.

Wong, L M and Elkordy, Amal (2013) Improvement of dissolution of Ibuprofen via in-situ lyophilisation. In: UK-PharmSci 2013 conference, 2 - 4 Sep 2013, Edinburgh, UK..

Rusby, N and Elkordy, Amal (2013) Influences of Poly-vinyl pyrrolidone and Pluronic® F127 on Lysozyme Folding Reversibility and Biological Activity. In: UK-PharmSci 2013 conference, 2 - 4 Sep 2013, Edinburgh, UK.

Suliman, A S, Anderson, Rosaleen and Elkordy, Amal (2013) Liquisolid Tablet Preparation for Norfloxacin Dissolution Enhancement. In: UK-PharmSci 2013 conference,, 2 - 4 Sep 2013, Edinburgh, UK..

Loh, Z and Elkordy, Amal (2013) Preparation and Characterisation of Metronidazole Floating Tablets. In: UK-PharmSci 2013 conference, 2 - 4 Sep 2013, Edinburgh, UK..

Javaheri, H, Elkordy, Amal and Carter, Paul (2013) Preparation and Evaluation of Liquisolid Compacts Containing Salbutamol Base with PEG 400 and Synperonic® PE/L44. In: UK-PharmSci 2013 conference, 2 - 4 Sep 2013, Edinburgh, UK.

Haj-Ahmad, Rita, Chaw, Cheng, Elkordy, Amal and Moore, Adrian (2013) Stabilizing effect of surfactants and saccharides on freeze dried lysozyme. In: UK-PharmSci 2013 conference, 2 - 4 Sep 2013, Edinburgh, UK..

Elkordy, Amal (2013) Folding reversibility of lysozyme in the presence of poly vinyl pyrrolidone. In: 2nd Central and Eastern European Conference on Thermal Analysis and Calorimetry, 27 - 30 Aug 2013, Vilnius, Lithuania.

Javaheri, H, Elkordy, Amal and Carter, Paul (2013) Preparation and Evaluation of Liquisolid Compacts Containing Griseofulvin with Synperonic® PE/L44 and Cremophor® ELP. In: 2013 UKICRS Symposium, 16 Apr 2013., University of Reading, Reading.

Elkordy, Amal (2013) Correlation of folding reversibility with biological activity: Lysozyme and Trysine in crystallised and dried forms. In: Modern Thermal Methods from an Industrial and Academic Perspective, 9-10 Apr 2013, Greenwich University, Chatham.

Elkordy, Amal (2012) Correlation of folding reversibility as determined by microcalorimetry with biological activity as determined by enzymatic assay: Lysozyme and Trysine in dried forms with excipients. In: Thermal and Spectroscopic Characterisation of Higher Order Structure of Biomolecules symposium, 24th October 2012, Royal Society of Chemistry, London, UK. (Unpublished)

Elkordy, Amal (2012) Two in one: Liquisolid technique to prepare fast disintegrating compacts. In: Target Meeting’s Second World Drug Discovery On-line conference, 16th-19th October 2012, On-line. (Unpublished)

Eng, Matthew, Haj-Ahmad, Rita Rochdi and Elkordy, Amal (2012) Characterisation of DNA in the presence of excipients. In: UK PharmSci 2012 conference, 12-14 Sep 2012, East Midlands Conference Centre, Nottingham University, Nottingham, UK.. (Unpublished)

Elkordy, Amal (2012) Effects of drying technology and polymers on integrity and biological activity of proteins. In: International Conference and Exhibition on Biowaivers & Biosimilars, September 10-12, 2012, Hilton San Antonio Airport, Texas, USA. (Unpublished)

Haj-Ahmad, Rita Rochdi, Chaw, Cheng, Elkordy, Amal and Moore, Adrian (2012) Pluronic F-127 as a constituent of niosomes as a novel delivery system for Insulin. In: UK PharmSci 2012 conference, September 12-14th, 2012, East Midlands Conference Centre, Nottingham University, Nottingham, UK.. (Unpublished)

Mamayusupov, Mahmud, Shabir, Mohammed and Elkordy, Amal (2012) Spray drying and vinyl polymers enhance biological activity and folding reversibility of proteins. In: UK PharmSci 2012 conference, September 12-14th, 2012, East Midlands Conference Centre, Nottingham University, Nottingham, UK.. (Unpublished)

Elkordy, Amal (2012) When will liquisolid tablets as dosage forms for enhancement dissolution of hydrophobic drugs be available in the market? In: 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 19-22 Mar 2012, Turkey, Istanbul.

Phang, K and Elkordy, Amal (2011) Spray freeze drying of trypsin with sugars. In: 2011 American Association of Pharmaceutical Scientists Annual Meeting and Exposition, Oct 23-27 2011, Washington DC , USA. (Unpublished)

Elkordy, Amal (2011) Protein Formulations: Challenges and Solutions. In: Target Meeting’s first World drug discovery on line conference: Track 1: Biotechnology and pharmaceutical research; session 3: Biotechnology and biopharmaceuticals- Part II., 20-22 Oct 2011, N/A-online event. (Unpublished)

Kwiek, A and Elkordy, Amal (2011) Characterisation of DNA formulations with alpha- and gamma-cyclodextrins in addition to polymer and lipid. In: The Science of Medicines: UK Pharmsci 2011, 31 Aug - 2 Sep 2011, East Midlands Conference Centre, Nottingham University, Nottingham. (Unpublished)

Elkordy, Amal, Javaheri, H., Hussain, I. and Essa, E.A. (2011) Characterisation of liquisolid tablets containing griseofulvin. In: The Science of Medicines: UK PharmSci 2011, 31 Aug-02 Sept 2011, East Midlands Conference Centre, Nottingham University, Nottingham. (Unpublished)

Hussain, R. and Elkordy, Amal (2011) Dissolution of naproxen microcrystals. In: The Science of Medicines: UK Pharmsci 2011, 31 Aug - 2 Sep 2011, East Midlands Conference Centre, Nottingham University, Nottingham. (Unpublished)

Zainal, N., Elkordy, Amal and Elkordy, Eman Ali (2011) Formulation and characterisation of fast disintegrating tablets with naproxen. In: The Science of Medicines: UK PharmSci 2011, 31 Aug-02 Sept 2011, East Midlands Conference Centre, Nottingham University, Nottingham. (Unpublished)

Wong, N and Elkordy, Amal (2011) Crystallisation of lysozyme with lactitol and lutrol F68. In: American Association of Pharmaceutical Scientists Annual Meeting and Exposition, 23-27 Oct 2011, Washington, DC , USA. (Unpublished)

Elkordy, Amal (2011) Cyclodextrin with pluronic as gene delivery systems. In: BioConference Live, Online event. (Unpublished)

Haj Ahmad, R, Chaw, Cheng, Moore, Adrian and Elkordy, Amal (2011) Effect of excipients on lysozyme crystals. In: The Science of Medicines: UK Pharmsci 2011, 31 Aug - 2 Sep 2011, East Midlands Conference Centre, Nottingham University, Nottingham. (Unpublished)

Arrigan, Elaine and Elkordy, Amal (2011) Ibuprofen liquisolid compacts. In: 2011 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition “Look Toward the Next 25 Years”, 23-27 Oct 2011, Walter E Washington Convention Center, Washington, DC, USA. (Unpublished)

Ebhabha, V, McGarry, Kenneth and Elkordy, Amal (2009) The effects of surfactants on hydrophobic drug dissolution and their statistical analysis. In: The British Pharmaceutical Conference, 6-9 Sept 2009, Manchester. (Unpublished)

Book

Elkordy, Amal (2023) Formulation of Monoclonal Antibody Therapies: From Lab to Market. Elsevier. ISBN 9780128233658

Elkordy, Amal (2013) Application of Calorimetry in a Wide Context - Differential Scanning Calorimetry, Isothermal Titration Calorimetry and Microcalorimetry. InTech. ISBN 978-953-51-0947-1

This list was generated on Mon Feb 26 04:45:38 2024 GMT.
  • Development of different tablet dosage forms to enhance, target and to sustain the dissolution of drugs
  • Formulation of gene therapeutics
  • Liposomal drug delivery systems
    • Preparation and characterisation of stable protein and monoclonal antibody formulations. For my experience in this area, I have been driven to write a book on monoclonal antibodies for the following:

    • Monoclonal antibodies are our personal assistants. At the start of the Covid-19 pandemic there were no effective treatments for such a new and destructive disease. This unfortunately resulted in many people across the world who were infected with this virus suffering, or even worse losing their lives. Fortunately, some patients with mild to moderate infection managed to tolerate and recover from this disease via their immune systems fighting to remove the virus from the body. One of the ways the immune system accomplishes this is by producing natural weapons in response to infection.

    • These natural weapons are known as monoclonal antibodies which serve the purpose of assisting the body in attacking external disease and threats to the body’s health. These monoclonal antibodies are very specific to target, in the case of the invading Covid-19 virus target particles, antibodies attack the virus and so block it from attacking the cells of the body and causing disease, therefore neutralising the threat, which is then cleared from the body.

      Each person’s immune system differs from one another. Some people have immune systems that can naturally produce enough monoclonal antibodies to fight against a virus, however, some people cannot naturally produce enough monoclonal antibodies to fight against disease and infection, which allows the disease to progress to severe stages.

    • On February 2021, the Drug and Food Administration agency, FDA, authorised the emergency use of combined bamlanivimab and etesevimab therapy for patients with mild to moderate Covid-19 which reduced the risk of Covid-19 hospitalisation and hence prevented the risk of disease progression. This inspired me to edit and write a textbook on this hot topic “Formulation of  Monoclonal Antibody Therapies: From Lab to Market” with the aim of benefiting students, academics, and scientists in understanding the field and the applications of monoclonal antibodies in this field.

    • Monoclonal antibodies are biological protein-based therapies. They are very complex drug molecules. There are many challenges associated with having them in suitable, effective, safe, and stable dosage forms. Although monoclonal antibodies are the most rapidly growing class of biological medicines, being complex with unique structure features means there are only a small number of approved monoclonal antibodies that can be used in clinics, and up until now the injectable dosage form is the only available method of administration of these medicines.

    • This book gives insights based on literature into other possible non-invasive routes of administration for monoclonal antibodies such as inhalation and transdermal routes. The textbook aims to enhance the knowledge on monoclonal antibodies, answering questions such as What are they? How can they be engineered in laboratories using living organisms? What is their mechanism of actions for managing difficult-to-treat diseases such as cancer, infections, autoimmune diseases for example rheumatoid arthritis, and most recently (in 2021) the FDA-approved monoclonal antibody that is being used in the treatment of Alzheimer’s disease?

    • Other questions this textbook aims to enhance the knowledge of include How their shelf lives can be extended? What are the most suitable types of packaging to keep them therapeutically effective? and What are the approved and marketed monoclonal antibody medicines and their clinical application? Each chapter of the book has co-author/s who contributed to the success of the completion of this textbook in a timely manner. 

    For more information about my areas of expertise, please refer to my Google Scholar.

Keynote speaker:

  • Application of self-assembled polymers and surfactants in drug delivery
    Presented at the EMN Meeting on Hydrogel Materials 2017, 24-28 April 2017, Amsterdam, Netherlands

    Invited speaker:

    • Floating and liposomal drug delivery systems to treat Helicobacter Pylori. Presented Virtually, Faculty of Pharmacy, Ninevah University, Iraq, 24 May 2023
    • Analysis of monoclonal antibodies at Biologics 2023, London, UK, 30-31 March 2023
    • Liposomes as gene therapeutics and as carriers to treat Helicobacter Pylori. Presented at Virtual Scientific Conference of Faculty of Pharmacy – Tanta University, Egypt, 10-11 October 2020
    • Liposomal gene delivery systems using microfluidic technology 
        Presented at EPSRC EHDA Network, 2nd Pharmaceutical Technology conference 2017, 14 July 2017, UCL, London, UK 
    • Spray drying technology to facilitate Naproxen dissolution 
      Presented at EuroPPS-2017 conference, June 2017, Valencia, Spain
    • Liposomal Drug Delivery Systems to Treat Helicobacter Pylori
      Presented at the '3rd EPSRC EHDA Network Meeting', 6 September 2016. Premier Inn Hotel, Glasgow
    • Is there a considerable need for biosimilars?
      Presented at 2nd Annual Biosimilars and Biobetters Congress, 3-4 April 2014, London
    • Evaluation of different Floating Tablets
    • Presented at Target meeting's Third World Drug Discovery online conference, 15-17 October 2013
    • Folding reversibility of lysozyme in the presence of polyvinyl pyrrolidone
      Presented at the 2nd Central and Eastern European Conference on Thermal Analysis and Calorimetry, 27-30 August 2013, Vilnius, Lithuania
    • Correlation of folding reversibility with biological activity: Lysozyme and Trysine in crystallised and dried forms
      Presented at TAC 2013 Conference Modern Thermal Methods from an Industrial and Academic Perspective, 9-10 April 2013, University of Greenwich, Chatham, UK
    • Effects of drying technology and polymers on integrity and biological activity of proteins
      Presented at International Conference and Exhibition on Biowaivers and Biosimilars, 12 September 2012, San Antonio, USA
    • Two in one: Liquisolid technique to prepare fast disintegrating compacts
      Presented at Target Meeting’s Second World drug discovery online conference, 16 October 2012
    • Protein formulations: Challenges and solutions
      Presented at Target Meeting’s first World Drug Discovery online conference, 22 October 2011
    • Cyclodextrin with pluronic as gene delivery systems
      Presented at BioConference Live, 22 March 2011
    • Servants of Life: From Discovery to Delivery
      Welsh School of Pharmacy, Cardiff (2009)
    • Application of Microcalorimetry (High Sensitivity Differential Scanning Calorimetry) to Detect Protein Conformational Stability
      Presented at Applications of BioCalorimetry Conference (abc6), Heidelberg, Germany (2008)


    Awards:

    • Commended oral presentation award in the session of short talks on ‘New developments in the pharmaceutical sciences’, British Pharmaceutical Conference, 2004
    • Commended poster award, British Pharmaceutical Conference, 2002


    Membership of professional bodies:

    • Member, Egyptian Pharmaceutical Society
    • Member, Academic Pharmacy Group and Industrial Pharmacy Liaison Group of the Royal Pharmaceutical Society of Great Britain
    • Member, International Society of Lyophilization – Freeze Drying 
    • Member, UK and Ireland Controlled Release Society 


    Membership of external organisations:

    • Fellow, Higher Education Academy (HEA)
    • Advance HE, External Examiners Directory
    • Included in Who's Who in the World (2010), 28th edition


    Event organiser:

    • EPSRC/EHDA Network event to explore pharmaceutical innovation, 3 February 2017, National Glass Centre, University of Sunderland.

Last updated 22 February 2024